abstract：BACKGROUND:The loss of the notochordal cells from the nucleus pulposus is associated with ageing and disc degeneration. However, understanding the mechanisms responsible for the loss of these cells has been hampered in part due to the difficulty of culturing and maintaining their phenotype. Furthermore, little is known...

journal_title：Biomedical engineering online

authors： Mwale F,Wang HT,Petit A,Girard-Lauriault PL,Hunter CJ,Ouellet JA,Wertheimer MR,Antoniou J

更新日期：2007-09-06 00:00:00

abstract：BACKGROUND:State-of-the-art signal processing methods are known to detect information in single-trial event-related EEG data, a crucial aspect in development of real-time applications such as brain computer interfaces. This paper investigates one such novel approach, evaluating how individual classifier and feature sub...

journal_title：Biomedical engineering online

authors： Aberg MC,Wessberg J

更新日期：2007-08-23 00:00:00

abstract：BACKGROUND:Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and increased "breathiness". Modelling and surrogate data studies have s...

journal_title：Biomedical engineering online

authors： Little MA,McSharry PE,Roberts SJ,Costello DA,Moroz IM

更新日期：2007-06-26 00:00:00

abstract：BACKGROUND:Perfluorocarbon (PFC) vapour in the expired gases during partial liquid ventilation should be prevented from entering the atmosphere and recovered for potential reuse. This study aimed to determine how much PFC liquid could be recovered using a conventional humidified neonatal ventilator with chilled condens...

journal_title：Biomedical engineering online

authors： Dunster KR,Davies MW,Fraser JF

更新日期：2007-05-31 00:00:00

abstract：BACKGROUND:Human embryonic stem cells (hESCs) are a potential source of cells for use in regenerative medicine. Automation of culturing, monitoring and analysis is crucial for fast and reliable optimization of hESC culturing methods. Continuous monitoring of living cell cultures can reveal more information and is faste...

journal_title：Biomedical engineering online

authors： Narkilahti S,Rajala K,Pihlajamäki H,Suuronen R,Hovatta O,Skottman H

更新日期：2007-04-12 00:00:00

abstract：BACKGROUND:Realistic modeling of cardiac inter-beat (RR) intervals is highly desirable for basic research in cardiac electrophysiology, clinical management of heart diseases, and developing signal processing tools for ECG analysis. METHODS:We present an open source computer model that is capable to generate realistic ...

journal_title：Biomedical engineering online

authors： Lian J,Clifford GD,Müssig D,Lang V

更新日期：2007-03-02 00:00:00

abstract：BACKGROUND:Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length. They are variable in the reproducibility to determine the muscle contraction at this length, and often do not maintain precise conditions during the examination. Conse...

journal_title：Biomedical engineering online

authors： Rahe-Meyer N,Weilbach C,Karst M,Pawlak M,Ahmed A,Piepenbrock S,Winterhalter M

更新日期：2007-01-02 00:00:00

abstract：BACKGROUND:We sought to compare uterine cervical electrical impedance spectroscopy measurements employing two probes of different sizes, and to employ a finite element model to predict and compare the fraction of electrical current derived from subepithelial stromal tissue. METHODS:Cervical impedance was measured in 1...

journal_title：Biomedical engineering online

authors： Gandhi SV,Walker DC,Brown BH,Anumba DO

更新日期：2006-11-24 00:00:00

abstract：BACKGROUND:Clinical studies suggest that local wall shear stress (WSS) patterns modulate the site and the progression of atherosclerotic lesions. Computational fluid dynamics (CFD) methods based on in-vivo three-dimensional vessel reconstructions have recently been shown to provide prognostically relevant WSS data. Thi...

journal_title：Biomedical engineering online

authors： Wellnhofer E,Goubergrits L,Kertzscher U,Affeld K

更新日期：2006-06-14 00:00:00

abstract：:Radiofrequency ablation is an interventional technique that in recent years has come to be employed in very different medical fields, such as the elimination of cardiac arrhythmias or the destruction of tumors in different locations. In order to investigate and develop new techniques, and also to improve those current...

journal_title：Biomedical engineering online

authors： Berjano EJ

更新日期：2006-04-18 00:00:00

abstract：BACKGROUND:The structure of the anatomical surfaces, e.g., CSF and gray and white matter, could severely influence the flow of volume currents in a head model. This, in turn, will also influence the scalp potentials and the inverse source localizations. This was examined in detail with four different human head models....

journal_title：Biomedical engineering online

authors： Ramon C,Schimpf PH,Haueisen J

更新日期：2006-02-08 00:00:00

abstract：BACKGROUND:Regional differences in action potential duration (APD) restitution in the heart favour arrhythmias, but the mechanism is not well understood. METHODS:We simulated a 150 x 150 mm 2D sheet of cardiac ventricular tissue using a simplified computational model. We investigated wavebreak and re-entry initiated b...

journal_title：Biomedical engineering online

authors： Clayton RH,Taggart P

更新日期：2005-09-20 00:00:00

abstract：:Herman P. Schwan [1915-2005] was a distinguished scientist and engineer, and a founding father of the field of biomedical engineering. A man of integrity, Schwan influenced the lives of many, including his wife and children, and his many students and colleagues. Active in science until nearly the end of his life, he w...

journal_title：Biomedical engineering online

authors： Foster KR

更新日期：2005-03-25 00:00:00

abstract：BACKGROUND:A specific problem using the public access defibrillators (PADs) arises at the railway stations. Some countries as Germany, Austria, Switzerland, Norway and Sweden are using AC railroad net power-supply system with rated 16.7 Hz frequency modulated from 15.69 Hz to 17.36 Hz. The power supply frequency contam...

journal_title：Biomedical engineering online

authors： Christov II,Iliev GL

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:Aging has been shown to slow reflexes and increase reaction time to varied stimuli. However, the effect of Type II diabetes on these same reaction times has not been reported. Diabetes affects peripheral nerves in the somatosensory and auditory system, slows psychomotor responses, and has cognitive effects o...

journal_title：Biomedical engineering online

authors： Richerson SJ,Robinson CJ,Shum J

更新日期：2005-02-21 00:00:00

abstract：BACKGROUND:Laser Interstitial ThermoTherapy (LITT) is a well established surgical method. The use of LITT is so far limited to homogeneous tissues, e.g. the liver. One of the reasons is the limited capability of existing treatment planning models to calculate accurately the damage zone. The treatment planning in inhomo...

journal_title：Biomedical engineering online

authors： Mohammed Y,Verhey JF

更新日期：2005-01-04 00:00:00

abstract：BACKGROUND:Analysis of heart rate variation (HRV) has become a popular noninvasive tool for assessing the activities of the autonomic nervous system (ANS). HRV analysis is based on the concept that fast fluctuations may specifically reflect changes of sympathetic and vagal activity. It shows that the structure generati...

journal_title：Biomedical engineering online

authors： Acharya U R,Kannathal N,Sing OW,Ping LY,Chua T

更新日期：2004-07-20 00:00:00

abstract：BACKGROUND:A computational model of myocardial energy metabolism was used to assess the metabolic responses to normal and reduced myocardial blood flow. The goal was to examine to what extent glycolysis and lactate formation are controlled by the supply of glycolytic substrate and/or the cellular redox (NADH/NAD+) and ...

journal_title：Biomedical engineering online

authors： Salem JE,Stanley WC,Cabrera ME

更新日期：2004-06-02 00:00:00

abstract：BACKGROUND:The bioluminescent enzyme firefly luciferase (Luc) or variants of green fluorescent protein (GFP) in transformed cells can be effectively used to reveal molecular and cellular features of neoplasia in vivo. Tumor cell growth and regression in response to various therapies can be evaluated by using biolumines...

journal_title：Biomedical engineering online

authors： Cong W,Wang LV,Wang G

更新日期：2004-05-04 00:00:00

abstract：BACKGROUND:Near infrared (NIR) light has been used widely to monitor important hemodynamic parameters in tissue non-invasively. Pulse oximetry, near infrared spectroscopy, and diffuse optical tomography are examples of such NIR light-based applications. These and other similar applications employ either lasers or light...

journal_title：Biomedical engineering online

authors： Bozkurt A,Onaral B

更新日期：2004-03-22 00:00:00

abstract：BACKGROUND:Extracting features from the colonoscopic images is essential for getting the features, which characterizes the properties of the colon. The features are employed in the computer-assisted diagnosis of colonoscopic images to assist the physician in detecting the colon status. METHODS:Endoscopic images contai...

journal_title：Biomedical engineering online

authors： Tjoa MP,Krishnan SM

更新日期：2003-04-08 00:00:00

abstract：BACKGROUND:It is generally accepted that cartilage adaptation and degeneration are mechanically mediated. Investigating the swelling behaviour of cartilage is important because the stress and strain state of cartilage is associated with the swelling and deformation behaviour. It is well accepted that the swelling of so...

journal_title：Biomedical engineering online

authors： Wu JZ,Herzog W

更新日期：2002-12-19 00:00:00

abstract：BACKGROUND:Computer-assisted arrhythmia recognition is critical for the management of cardiac disorders. Various techniques have been utilized to classify arrhythmias. Generally, these techniques classify two or three arrhythmias or have significantly large processing times. A simpler autoregressive modeling (AR) techn...

journal_title：Biomedical engineering online

authors： Ge D,Srinivasan N,Krishnan SM

更新日期：2002-11-13 00:00:00